Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor used in the remedy of various myeloma. Its synthesis or review is critical for making sure the purity and safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the procedure of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets specific types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is vital for optimizing the manufacturing process and making sure higher purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilised to deal with breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast cancer. Different intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in treating cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the procedure of colorectal most cancers and compact cell lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound CAS NO. 137281-39-1 is associated with the synthesis of adamantane derivatives, that have a variety of programs, together with antiviral properties.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, 3-(4-Nitro-1-oxo-1 an oral drug for kind two diabetic issues that inhibits the enzyme DPP-4 to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of varied gluconic acid derivatives, which are used in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication applied to manage sort 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).